TREASURE-CKD

TREASURE-CKD (NCT05536804) is an ongoing Eli Lilly-sponsored mechanistic trial of tirzepatide in participants with overweight or obesity and chronic kidney disease (CKD), with or without Type 2 diabetes. It is designed to assess tirzepatide’s effects on kidney function — specifically eGFR slopes and UACR changes — in a CKD-enriched population, likely including patients with lower eGFR than the SURPASS programme enrolled. Results are expected to be the first prospective data on tirzepatide in patients approaching eGFR <30. No results published as of April 2026.

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