- What are the patch-test positivity rates and top allergens specifically in children aged 1–4 with AD (most series report 0–14 or 0–18 together; Italian 0–<3 group was 22.0% but n=59)?
- Is there any validated patch-test series or reduced-concentration protocol for under-6s, given no commercial panel is FDA-indicated below age 6?
- Do any controlled data quantify how often parent-applied tea tree or lavender oil on eczematous toddler skin leads to new sensitisation (vs adult/occupational series)?
- Does the AD–contact allergy relationship differ by allergen type (MCI/MI lower in AD per US registry vs higher per Italian data) and by AD control at time of testing?