Conflicts — emollient-chemistry (round 12)

  • Petrolatum and barrier repair: [Ghadially et al., JAAD, 1992] says petrolatum permeates the stratum corneum and accelerates barrier recovery. [Elias & Wakefield, Clin Rev Allergy Immunol, 2011] says non-physiologic lipids such as petrolatum impede rather than correct the underlying barrier defect. Unresolved. (wiki/Petrolatum.md)
  • Linoleic-rich oils on infant skin: [Vaughn et al., 2018; Danby et al., 2013] say high-linoleic sunflower oil supports barrier repair. [Cooke et al., Acta Derm Venereol, 2016] found sunflower oil, like olive oil, slowed lipid-lamellae maturation in 115 newborns. Unresolved. (wiki/Linoleic Acid.md)
  • GLA in combination supplements: [Niseteo et al., Nutrients, 2024] says omega-3 + blackcurrant GLA + vitamin D cut SCORAD in 52 children. [Bamford et al., Cochrane, 2013] says oral GLA oils are no better than placebo in 27 RCTs. Unresolved. (wiki/Gamma-Linolenic Acid.md)
  • Bio vs non-bio detergent: [Andersen 1998; Basketter 2008] say enzyme detergents do not worsen AD. Parent reports (anecdotal, r/toddlers 2024) credit non-bio switch. Unresolved. (wiki/Laundry Detergents.md)