Outcomes Comparison — open questions

• How much do UK/US families spend out of pocket on home/herbal remedies for a toddler specifically? No study located (Johnston 2003 reports use, not spend; “Santer 2016” CAM survey named in the brief was not located).
• How quickly do toddler flares respond to mild TCS vs Track A remedies? No paediatric time-to-response comparison found; only trial endpoint durations (7 days–16 weeks).
• Is twice-weekly proactive TCS/TCI cost-effective in 1–4-year-olds under current NHS prices (Healy 2011 model not retrieved)? And what are current NHS prices for Elidel and US prices for dupilumab?